Products & Technology

Science

VMT-𝛼-GEN is a production device that enables a nimble supply of therapeutic radioisotope with the power of alpha-particle therapy for cancer.

In order to build a fully integrated alpha-particle radiopharmaceutical business, Viewpoint is securing the supply of therapeutic Pb-212 radioisotope for medical centers and regional radiopharmacies. To achieve this distinction, Viewpoint is developing its own proprietary benchtop production device (VMT-𝛼-GEN) for delivering alpha-particle therapeutic isotope Pb-212. With a half-life of 10.6 hours, Pb-212 is ideally suited to deliver powerful alpha-particle therapy to cancerous tumors, while representing a lower risk for off-target unintended effects and the potential for treatment on an outpatient basis.

Radionuclide generators such as VMT-𝛼-GEN are used commonly in radiopharmacies and nuclear medicine facilities across the world. The devices share a common characteristic of enabling the production of a purified chemical form of the radionuclide needed that can be easily combined with the ligand that seeks out cancerous tumors. Because the shelf life of VMT-𝛼-GEN is based on a longer-lived radionuclide (Ra-224), a single shipment of VMT-𝛼-GEN can be used to produce radiopharmaceutical doses daily, for up to a week. The device can then be returned to the manufacturer in approved packaging to eliminate radioactive waste from the medical center or radiopharmacy.

Viewpoint is establishing centrally located facilities in the United States with the goal of enabling overnight shipments of a nimble supply of both its Pb-203 radiopharmaceutical imaging agents and cancer-targeted Pb-212 alpha-particle therapeutics for personalized image-guided therapies anywhere in the United States.

Viewpoint Molecular Targeting is a radiopharmaceutical company developing precision oncology therapeutics and complementary diagnostic imaging agents. The Company’s leading alpha-particle radiotherapies are designed to deliver powerful alpha radiation specifically to cancer cells utilizing specialized targeting peptides. Viewpoint is also developing complementary diagnostics that utilize the same targeting peptide which provide the opportunity to personalize treatment and optimize patient outcomes. This "theranostic” approach enabling the ability to see the specific tumor and then treat it to potentially improve efficacy and minimize toxicity associated with many other types of cancer treatments.